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教員紹介

所属 薬学部 薬学科 教授
氏名 古川 淳
最終学歴 東京大学大学院薬学系研究課博士課程修了
現在所属している学会 アメリカ化学会
学士・修士・博士 薬学博士
所有資格 薬剤師
研究の分野 薬学
主な研究項目 医薬品化学
主な研究業績 1. Isolation, Structure and Synthesis of Hirsutene,a Precursor Hydrocarbon of Coriolin Biosynthesis /Tetrahedron lett.,3125(1971)/共著/1971.01
2.Isolation of 6- Protoilludene and the related Alchols /Tetrahedron lett.,1381(1977)/共著/1977.01
5.Method for Determination of Enantiomeric Composition and Absolute Configuration of 2,3-Deuterated 3-Alkylpropanols /Tetrahedron lett.,24(47),5257-5260.1983/共著/1983.01
6.Eu(fod)3-shifted 2H-NMR as a Probe of Chirality due to Deuterium Substiution; Stereospecific Deuterium Incorporation into 2-n-Hexy-5-n-Propylresorcinol,a Polyketide Produced by Pseudomonas Sp.B-9004 /Tetrahedron lett.,24(47),5261-5264.1983/共著/1983.01
4.Characterization of Methyl Glycosides at the Pico-to Nano-gramleve1 /Carbohydrate Research,118(1983)135-146/共著/1983.01
7.Studies on Macrocyclic Lactone Antibiotics VII. Structure of a Phytotoxine "Rhizoxin" produced by Rhizopus Chinensis /J.Antibiotics,37(4),354-362.1984/共著/1984.01
13.Conversion of 6-Protoilludene into Illudin-M and-S by Omphalotus olearius /Tetrahedron Lett.,26(39),4755-4758.1985/共著/1985.01
15.Stereochemistry of 2-Aminopimeric Acids in Three Species of Asplenium /Phytochemistry,24(10),2291-2294,1985/共著/1985.01
12.Synthesis of dl-6-Protoilludene /Chem.Pharm.Bull.,33(1),440-443(1985)/共著/1985.01
14.Isolation and Structure of Tunichrome B-1,a Reducing Blood Pigment from The Tunicate Ascidia nigra L. /J.Am.Chem.Soc.,1985,107(18),5298-5300/共著/1985.01
11.Synthesis of 8-Hydroxy-6-Protoilludene,a Probable Biosynthetic Intermediate of Humulene-Derived Sesquiterpenes Produced by Basldiomycetes /Chem.Pharm.Bull.,33(7),2783-2791(1985)/共著/1985.01
8.αー(Hydroxymethyl)serine from Visia pseudo-orobus /Phytochemistry,24(4),853-854,1985/共著/1985.01
9. 3,4-Dihydroxy-2-Hydroxymethylpyrrolididine from Arachniodes Standishii /Phytochemistry,24(3),593-594.1985/共著/1985.01
10.Epimerization of 6-Protoilluden-8-one at C-3 and the Relative Thermodynamic Stabilities of Stereoisomeric 6-Protoilluden-8-ones /Chem.Pharm.Bull.,33(7),2792-2797(1985)/共著/1985.01
18.The Structure of Neo-Enactin A, a New Antifungal Antibiotic Potenciating Polyene Antifungal Antibiotics /J.Antibiotics,39(5),717-720,1986/共著/1986.01
19.Stereospeclific Deuterium incorporation into 11-Cyclohexylundecaoic Acid from S-[6,6-2H2]-Glucose by Curtobacterium pusilum /Chem.Pharm.Bull.34(12),5176-5179(1986)/共著/1986.01
17.Isolation of Tunichrome B-1,a Reducing Blood Pigment of the Sea Squirt, Ascidia nigra /J.Natural Products,49(2),193-204,1986/共著/1986.01
16.The Effect of Rice Plant Components on Rice Plant Pathogrn.I.Isolation of Anastomosis Promoting Factors for Conidia of G.oryzae from a Rice Plant(1) /Yakugaku Zasshi,106(5),383-390.1986/共著/1986.01
21.Cyclobutyl Cation Rearrangements of 6-Protoilluden-8α-ol,7-Protoilluden-6-ol and Related Compouds /Chem. Pharm. Bull.,35(7)1987 2678-2685 /共著/1987.01
20.Isolation,Structural Elucidation and Biological Properties of Neoenactins B1,B2,M1 and M2,Neoenactin Congeners /J.Antibiotics,40(3)1987 266-274/共著/1987.01
22.A New Versatile Synthesis of Cerulenin /Chem. Pharm. Bull.,36(3)1988 1229-1232 /共著/1988.01
23.A New Group of Antibiotics,Hydroxamic Acid Antimycotic Antibiotics II. Neo-Enactins NL1,NL2,and Structure-Activity Relatlonship /J.Antibiotics 40(3)1989 276-282/共著/1989.01
24.A New Group of Antibiotics,Hydroxamic Acid Antimycotic Antibiotics.IV. Structure of enactines Ia,Ib1,Ib2 and Va /Chem.Pharm.Bull.,39(6)1991 1436-1439/共著/1991.01
25.Syntheses of Cerulenin and its analogs.I. Cerulenin and Its Analogs with Modified Side Chain /Chem.Pharm.Bull.,40(11)1992 2945-2953/共著/1992.01
26.Effect of side-chain structure on inhibition of yeast fatty-acid synthase by cerulenin analogues /Eur.J.Biochem.,211,111-115(1993)/共著/1993.01
27.(2S)-2-Amino-5-chloro-4-hydeoxy-5-hexenoic acid,a new chloroamino acid, and related compouds from Amanita gymnopus /Mycosvience 35: 391-394,1994/共著/1994.01
主な担当授業科目名 有機薬化学Ⅰ、基礎薬化学特論Ⅱ

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