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教員紹介

所属 薬学部 薬学科 教授
氏名 鈴木 英治
最終学歴 東邦大学大学院薬学研究科修士課程
現在所属している学会 日本薬学会、有機合成化学協会、アメリカ化学会
学士・修士・博士 博士(薬学)
所有資格 薬剤師免許
研究の分野 化学系薬学 創薬科学 有機化学
主な研究項目 有機合成化学
主な研究業績 Chemoselective Benzylation of Unprotected Anthranilic Acids with Benzhydryl Alcohols by Water- Soluble Au(III) /TPPMS in Water. /Journal of Organic Chemistry 2013, 78(13), 6714-6720. /共著/
Development of a New Distyrylbenzene-Derivative Amyloid-β-aggregation and Fibril Formation Inhibitor. /Chem. Pharm. Bull. 2012, 60(9), 1164–1170. /共著/
Synthesis of VIP- lipopeptide using a new linker to modify liposomes: towards the development of a drug delivery system for active targeting. /Chemical & Pharmaceutical Bulletin 2013, 61(11), 1184-1187./共著/
Benzoyl methyl phosphates as efficient reagents in the one- pot tandem approach for the synthesis of 2-phenylbenzimidazoles in water. /RSC Advances 2014, 4(8), 3768-3773. /共著/
Mechanistic studies for synthesis of bis(indolyl) methanes: pd- catalyzed C- H activation of indole- carboxylic acids with benzyl alcohols in water. /Catalysts 2013, 3(2), 486-500/共著/
Au(III) /TPPMS- Catalyzed Benzylation of Indoles with Benzylic Alcohols in Water. /Journal of Organic Chemistry 2013, 78(23), 12128-12135./共著/
Pd-Catalyzed Benzylic C-H Amidation with Benzyl Alcohols in Water: A Strategy To Construct Quinazolinones /J. Org. Chem. 2012, 77 (16), 7046–7051. /共著/
N-Benzylation /Benzylic C-H Amidation Cascade by the (η3- Benzyl) palladium System in Aqueous Media: An Effective Pathway for the Direct Construction of 3- Phenyl- 3, 4-dihydro- (2H) - 1, 2, 4-benzothiadiazine 1, 1-Dioxides /ADVANCED SYNTHESIS & CATALYSIS 2013, 355, 2308 – 2320. /共著/
Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2, 3- dioxygenase (IDO) inhibitors. /Bioorganic & Medicinal Chemistry 2013, 21(5), 1159-1165. /共著/
A practical regioselective synthesis of alkylthio- or arylthioindoles without the use of smelly compounds such as thiols. /Chemical & Pharmaceutical Bulletin 2013, 61(3), 292-303./共著/
Fischer Indolization and Its Related Compounds. XVIII. Formation of Four Unexpected Angular Benz[e]indoles on Fischer Indolization of Ethyl Phenylpyruvate 2-[(1, 4-Dimethoxy-2-naphthyl)hydrazone] /Chem. Pharm. Bull, 1983, 31, 4391-4400./共著/1983.11
Fischer Indolization and Its Related Compounds. XIX. Synthesis of Ethyl 4-Methoxy- and Ethyl 5-Methoxy-1-phenyl-3H-benz[e]indole-2-carboxylates /Chem. Pharm. Bull, 1983, 31, 4401-4408./共著/1983.12
Formation of an Angular 5-Chlorobenz[e]indole by the Fischer Indolization of a 1-Methoxy-2-naphthylhydrazone: Correction of the Structure of the So-called Linear Ethyl 9-Methoxy-1H-benz[f]indole-2-carboxylate to the Angular Ethyl 5-Chloro-3H-benz[e]indole-2-carboxylate /J. Chem. Res., 1984 (S) 326-327, (M) 2974-2997./共著/1984.08
Regioselectivity in the Vilsmeier-Haack Reaction of N-Benzyl-1,2,3,4-tetrahydrocarbazole /Heterocycles, 1988, 27, 2341-2344./共著/1988.06
Palladium-catalyzed Reaction of 3-Bromoindole Derivative with Allyl Esters in the Presence of Hexa-n-butyldistannane /Heterocycles, 1990, 31, 1505-1511./共著/1990.04
A New General Synthetic Route for 1-Substituted 4-Oxygenated β-Carbolines /Chem. Pharm. Bull, 1991, 39, 2170-2172./共著/1991.04
A New Synthesis of Crenatine from Ethyl Indole-2-carboxylate /Chem. Pharm. Bull, 1991, 39, 2189-2195./共著/1991.05
Intramolecular Vinylation of Pyrrole Derivatives Using Palladium: a New Synthetic Method for Substituted Indoles /Chem. Pharm. Bull, 1991, 39, 2830-2836./共著/1991.07
Unexpected Debenzylation of N-Benzylindoles with Lithium Base. A New Method of N-Debenzylation. /Tetrahedron Lett., 1995, 36, 1671-1672./共著/1995.03
Synthetic Studies of 1,2,3,4-Tetrahydro-1,3,4-trioxo-β-carboline Alkaloids I /Heterocycles, 1996, 42, 83-86./共著/1996.01
Total Synthesis of the Structure Proposed for Picrasidine-H /Heterocycles, 1997, 46, 57-60./共著/1997.01
New Findings on the Hemetsberger-Knittel Reaction /Chem. Pharm. Bull, 1997, 45, 1739-1744./共著/1997.03
A General Synthetic Route for 1-Substituted 4-Oxygenated β-Carbolines /Tetrahedron, 1997, 53, 1593-1606./共著/1997.03
First Total Syntheses of 4, 8-Dioxygenated β-Carboline Alkaloids /J. Chem. Soc. Perkin Trans. 1, 1999, 1717-1723. /共著/1999.03
Unexpected Formation of Quinolone Derivatives in Reissert Indole Synthesis /Synlett, 2000, 1196-1198./共著/2000.03
SYNTHESIS OF NON-PEPTIDIC TRYPTAMINE DERIVATIVE (THS-12) WHICH STIMULATES TPO RESPONSIVE CELL GROWTH. /Heterocycles, 2002, 56, 519-524. /共著/2002.01
IMPROVED SYNTHESIS OF 7, 9-DIDECARBOXYMETHOXATHINE /Heterocycles, 2002, 56, 515-518. /共著/2002.01
THE VILSMEIER-HAACK REACTION ON METHYL HOMOLOGUES OF N-BENZYLTETRAHYDROCARBAZOLE /Heterocycles, 2003, 61, 225-235. /共著/2003.02
A Total Synthesis of 1-Methoxycanthin-6-one: An Efficient One-Pot Synthesis of the Canthin-6-one Skeleton from β-Carboline-1-carbaldehyde /Synthesis, 2005, 28-32. /共著/2005.01
A New Synthesis of 4-Oxygenated β-carboline Derivatives by Fischer Indolization /Tetrahedron Lett., 2005, 46, 3831-3834. /共著/2005.09
Isolation and Structure Assignment of an Iminotetrasaccharide from a Cultured Filamentous Cyanobacterium Anabaena sp. /J. Nat. Prod. 2006, 69, 365-368./共著/2006.02
Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance. /Chemical Biology & Drug Design 2007, 69, 356-361. /共著/2007.02
CHEMICAL CONFIRMATION OF THE STRUCTURE OF A MUTAGENIC AMINOPHENYLNORHARMAN, 9-(4-AMINOPHENYL)-9H-PYRIDO[3,4-b]INDOLE /Heterocycles 2010, 80, 455-462./共著/2010.03
SYNTHESIS AND EVALUATION OF 4-ARYL-2(1H)-QUINOLINONES AS POTENT AMYLOID β FIBRILLOGENESIS INHIBITORS. /Heterocycles 2012, 85(8), 1933-1940. /共著/2012.03
主な担当授業科目名 基礎有機化学、有機化学Ⅰ、化学系薬学特論、薬学総括講義Ⅰ(化学)

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