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教員紹介

所属 薬学部 薬学科 教授
氏名 根来 孝治
最終学歴 昭和大学大学院薬学研究科 博士号取得
現在所属している学会 日本免疫学会、日本薬学会
学士・修士・博士 博士(薬学)
所有資格 薬剤師免許
研究の分野 内科系臨床医学、基礎医学
主な研究項目 アレルギー疾患患者における制御性T細胞の機能異常
主な研究業績 免疫記憶CD4 T細胞の行方? /ファルマシア/単著/2001.12
Beneficial role of tetrahydrobiopterin on various cardiovascular diseases and regulation of its levels under pathological conditions.(査読付き) /Pteridines/共著/2006.03
Decay-accelerating factor /Nippon Rinsho/共著/2010.06
Bronchial Asthma-Emerging Therapeutic Strategies. Chapter 4; Immune mechanisms of childhood asthma(査読付き) /InTech/共著/2012.02
Improved method for the isolation and preliminary characterization of human DAF (decay-accelerating factor).(査読付き) /J Biochem/共著/1986.07
Induction of CD8+ suppressor T cells by treatment with DMBA and TPA in vitro.(査読付き) /Cell Immunol/共著/1991.12
Cellular induction mechanism of CD8+ suppressor T cells by DMBA and TPA: Formation of CD4+ suppressor-inducer T cells.(査読付き) /Cell Immunol/共著/1996.02
Induction of CD4+ regulatory T cells by 12-O-tetradecanoylphorbol 13-acetate in mice.(査読付き) /Int Immunopharmacol/共著/2001.06
Synergistic cytotoxic action of Vitamin C and Vitamin K3.(査読付き) /Anticancer Res/共著/2001.09
Induction of cell death by pro-oxidant action of Moxsa smoke.(査読付き) /Anticancer Res/共著/2002.01
Induction of CD4+ regulatory T cells by TPA in mice: contra-suppression by CD8+ T cells.(査読付き) /Biol Pharm Bull/共著/2002.02
Diverse biological activities of fermented pine seed shell extract.(査読付き) /Anticancer Res/共著/2002.05
Effect of tachykinins and histamine on the expression of thymus- and activation-regulated chemokine mRNA in peripheral blood mononuclear cells and human bronchial epithelial cells.(査読付き) /J Health Sci/共著/2002.09
Partial purification of cytotoxic substances from moxa extracts.(査読付き) /Anticancer Res/共著/2002.09
Interaction between dental metals and antioxidants, assessed by cytotoxicity assay and ESR spectroscopy.(査読付き) /Anticancer Res/共著/2002.11
Inhibition of NO production by activated macrophages by phenolcarboxylic acid monomers and polymers with radical scavenging activity.(査読付き) /Anticancer Res/共著/2003.03
Reduction of GTP cyclohydrolase I feedback regulating protein expression by hydrogen peroxide in vascular endothelial cells.(査読付き) /J Pharmacol Sci/共著/2005.02
Possible involvement of hydroxyl radical on the stimulation of tetra-hydrobiopterin synthesis by hydrogen peroxide and peroxynitrite in vascular endothelial cells.(査読付き) /Int J Biochem Cell Biology/共著/2005.04
A rapid up-regulation in UCP3 transcriptional activity in response to moderate intensity exercise in rat skeletal muscle.(査読付き) /J Sport Sci and Med/共著/2005.06
A novel enzyme-linked immunosorbent assay specific for high-molecular weight adiponectin.(査読付き) /J Lipid Res/共著/2006.07
Influence of SNPs in cytokine-related genes on the severity of food allergy and atopic eczema in children.(査読付き) /Pediatr Allergy Immunol/共著/2006.12
Analysis of students, achievement rate and contents of assessment for objecttive structured clinical examination (OSCE) attempted at the faculty of pharmaceutical sciences, Showa University.(査読付き) /Yakugaku Zsashi/共著/2007.05
TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. (査読付き) /Nat Med/共著/2008.07
Participation of Th17 and Treg cells in pediatric bronchial asthma.(査読付き) /J Health Sci/共著/2010.07
Impaired Ca2+ regulation of CD4+CD25+ regulatory T cells from pediatric asthma patients.(査読付き) /Int Arch Allergy Immunol/共著/2011.05
Low HCMV DNA copies can establish infection and result in significant symtoms in extremely preterm infants: a prospective study.(査読付き) /Am J Perinatol/共著/2012.05
Neutrophil TRPM2 channels are implicated in the exacerbation of myocardial ischaemia/reperfusion injury.(査読付き) /Cardiovasc Res/共著/2013.02
Adiponectin enhances calcium dependency of mouse bladder contraction mediated by protein kinase Ca expression.(査読付き) /J Pharmacol Exp Ther/共著/2013.04
Metformin modulates GLP-1- and GIP-mediated intracellular signaling under normoglycemic conditions.(査読付き) /Open J Endocr and Metab Dis/共著/2013.11
Potentiated macrophage activation by acid sensing under low adiponectin levels.(査読付き) /Mol Immunol/共著/2014.02
Elevated receptor for activated C kinase 1 expression is involved in intracellular Ca2+ influx and potentially associated with compromised regulatory T cell function in patients with asthma.(査読付き) /Clin Exp Allergy/共著/2014.09
A simple smart amplification assay for the rapid detection of human cytomegalovirus in the urine of neonates.(査読付き) /J Virol Methods/共著/2014.11
Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe2+ in human monocytic U937 cells.(査読付き) /Int J Biochem Cell Biology/共著/2015.11
TRPM2 channels in alveolar epithelial cells mediate bleomycin-induced lung inflammation.(査読付き) /Free Radic Biol Med/共著/2015.11
Suppressive Effects of Glucose-Dependent Insulinotropic Polypeptide on Cardiac Hypertrophy and Fibrosis in Angiotensin II-Infused Mouse Models /Circ J/共著/2016.08
The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection /Biochem Biophys Res Commun/共著/2016.11
Relationship of the cytokine SNPs and clinical characteristics in children with atopy.(査読付き) /Allergy Clin Immunol Int/共著/
サイトメガロウイルス感染症の薬物治療 /昭和学士会雑誌/共著/2013.06
主な担当授業科目名 薬物治療学Ⅲ、アドバンスセミナー1A

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