鈴木 英治
Faculty

学部・大学院

鈴木 英治

所属 薬学部 薬学科 教授
最終学歴 東邦大学大学院薬学研究科修士課程
現在所属している学会 日本薬学会、有機合成化学協会、アメリカ化学会
学士・修士・博士 博士(薬学)
所有資格 薬剤師免許
研究の分野 化学系薬学 創薬科学 有機化学
主な研究項目 有機合成化学
主な研究業績 SYNTHESIS AND EVALUATION OF 4-ARYL-2(1H)-QUINOLINONES AS POTENT AMYLOID β FIBRILLOGENESIS INHIBITORS./Heterocycles 2012, 85(8), 1933-1940./共著/2012.03
CHEMICAL CONFIRMATION OF THE STRUCTURE OF A MUTAGENIC AMINOPHENYLNORHARMAN, 9-(4-AMINOPHENYL)-9H-PYRIDO[3,4-b]INDOLE/Heterocycles 2010, 80, 455-462./共著/2010.03
Development of aggregation inhibitors for amyloid-β peptides and their evaluation by quartz-crystal microbalance./Chemical Biology & Drug Design 2007, 69, 356-361./共著/2007.02
Isolation and Structure Assignment of an Iminotetrasaccharide from a Cultured Filamentous Cyanobacterium Anabaena sp./J. Nat. Prod. 2006, 69, 365-368./共著/2006.02
A New Synthesis of 4-Oxygenated β-carboline Derivatives by Fischer Indolization/Tetrahedron Lett., 2005, 46, 3831-3834./共著/2005.09
A Total Synthesis of 1-Methoxycanthin-6-one: An Efficient One-Pot Synthesis of the Canthin-6-one Skeleton from β-Carboline-1-carbaldehyde/Synthesis, 2005, 28-32./共著/2005.01
THE VILSMEIER-HAACK REACTION ON METHYL HOMOLOGUES OF N-BENZYLTETRAHYDROCARBAZOLE/Heterocycles, 2003, 61, 225-235./共著/2003.02
SYNTHESIS OF NON-PEPTIDIC TRYPTAMINE DERIVATIVE (THS-12) WHICH STIMULATES TPO RESPONSIVE CELL GROWTH./Heterocycles, 2002, 56, 519-524./共著/2002.01
IMPROVED SYNTHESIS OF 7, 9-DIDECARBOXYMETHOXATHINE/Heterocycles, 2002, 56, 515-518./共著/2002.01
Unexpected Formation of Quinolone Derivatives in Reissert Indole Synthesis/Synlett, 2000, 1196-1198./共著/2000.03
First Total Syntheses of 4, 8-Dioxygenated β-Carboline Alkaloids/J. Chem. Soc. Perkin Trans. 1, 1999, 1717-1723./共著/1999.03
New Findings on the Hemetsberger-Knittel Reaction/Chem. Pharm. Bull, 1997, 45, 1739-1744./共著/1997.03
A General Synthetic Route for 1-Substituted 4-Oxygenated β-Carbolines/Tetrahedron, 1997, 53, 1593-1606./共著/1997.03
Total Synthesis of the Structure Proposed for Picrasidine-H/Heterocycles, 1997, 46, 57-60./共著/1997.01
Synthetic Studies of 1,2,3,4-Tetrahydro-1,3,4-trioxo-β-carboline Alkaloids I/Heterocycles, 1996, 42, 83-86./共著/1996.01
Unexpected Debenzylation of N-Benzylindoles with Lithium Base. A New Method of N-Debenzylation./Tetrahedron Lett., 1995, 36, 1671-1672./共著/1995.03
Intramolecular Vinylation of Pyrrole Derivatives Using Palladium: a New Synthetic Method for Substituted Indoles/Chem. Pharm. Bull, 1991, 39, 2830-2836./共著/1991.07
A New Synthesis of Crenatine from Ethyl Indole-2-carboxylate/Chem. Pharm. Bull, 1991, 39, 2189-2195./共著/1991.05
A New General Synthetic Route for 1-Substituted 4-Oxygenated β-Carbolines/Chem. Pharm. Bull, 1991, 39, 2170-2172./共著/1991.04
Palladium-catalyzed Reaction of 3-Bromoindole Derivative with Allyl Esters in the Presence of Hexa-n-butyldistannane/Heterocycles, 1990, 31, 1505-1511./共著/1990.04
Regioselectivity in the Vilsmeier-Haack Reaction of N-Benzyl-1,2,3,4-tetrahydrocarbazole/Heterocycles, 1988, 27, 2341-2344./共著/1988.06
Formation of an Angular 5-Chlorobenz[e]indole by the Fischer Indolization of a 1-Methoxy-2-naphthylhydrazone: Correction of the Structure of the So-called Linear Ethyl 9-Methoxy-1H-benz[f]indole-2-carboxylate to the Angular Ethyl 5-Chloro-3H-benz[e]indole-2-carboxylate/J. Chem. Res., 1984 (S) 326-327, (M) 2974-2997./共著/1984.08
Fischer Indolization and Its Related Compounds. XIX. Synthesis of Ethyl 4-Methoxy- and Ethyl 5-Methoxy-1-phenyl-3H-benz[e]indole-2-carboxylates/Chem. Pharm. Bull, 1983, 31, 4401-4408./共著/1983.12
Fischer Indolization and Its Related Compounds. XVIII. Formation of Four Unexpected Angular Benz[e]indoles on Fischer Indolization of Ethyl Phenylpyruvate 2-[(1, 4-Dimethoxy-2-naphthyl)hydrazone]/Chem. Pharm. Bull, 1983, 31, 4391-4400./共著/1983.11
Benzoyl methyl phosphates as efficient reagents in the one- pot tandem approach for the synthesis of 2-phenylbenzimidazoles in water./RSC Advances 2014, 4(8), 3768-3773./共著
Synthesis of VIP- lipopeptide using a new linker to modify liposomes: towards the development of a drug delivery system for active targeting./Chemical & Pharmaceutical Bulletin 2013, 61(11), 1184-1187./共著
Au(III) /TPPMS- Catalyzed Benzylation of Indoles with Benzylic Alcohols in Water./Journal of Organic Chemistry 2013, 78(23), 12128-12135./共著
Chemoselective Benzylation of Unprotected Anthranilic Acids with Benzhydryl Alcohols by Water- Soluble Au(III) /TPPMS in Water./Journal of Organic Chemistry 2013, 78(13), 6714-6720./共著
Mechanistic studies for synthesis of bis(indolyl) methanes: pd- catalyzed C- H activation of indole- carboxylic acids with benzyl alcohols in water./Catalysts 2013, 3(2), 486-500/共著
A practical regioselective synthesis of alkylthio- or arylthioindoles without the use of smelly compounds such as thiols./Chemical & Pharmaceutical Bulletin 2013, 61(3), 292-303./共著
Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2, 3- dioxygenase (IDO) inhibitors./Bioorganic & Medicinal Chemistry 2013, 21(5), 1159-1165./共著
N-Benzylation /Benzylic C-H Amidation Cascade by the (η3- Benzyl) palladium System in Aqueous Media: An Effective Pathway for the Direct Construction of 3- Phenyl- 3, 4-dihydro- (2H) - 1, 2, 4-benzothiadiazine 1, 1-Dioxides/ADVANCED SYNTHESIS & CATALYSIS 2013, 355, 2308 – 2320./共著
Pd-Catalyzed Benzylic C-H Amidation with Benzyl Alcohols in Water: A Strategy To Construct Quinazolinones/J. Org. Chem. 2012, 77 (16), 7046–7051./共著
Development of a New Distyrylbenzene-Derivative Amyloid-β-aggregation and Fibril Formation Inhibitor./Chem. Pharm. Bull. 2012, 60(9), 1164–1170./共著
主な担当授業科目名 基礎有機化学、有機化学Ⅲ、医薬品合成化学、薬学総括講義Ⅰ(化学)