金子 希代子
Faculty

学部・大学院

金子 希代子

所属 薬学部 薬学科 教授
最終学歴 東京大学大学院薬学系研究科生命薬学専攻修士課程修了
現在所属している学会 日本痛風•尿酸核酸学会、日本薬学会、日本尿路結石症学会、日本生化学会、日本臨床栄養学会、日本リウマチ学会
学士・修士・博士 東京大学薬学博士
所有資格 教員、薬剤師、第1種放射線取扱主任者
研究の分野 6802,7207,7307
主な研究項目 プリン代謝、機器分析
主な研究業績 総説 特集/心血管疾患の残余リスクとしてのキサンチンオキシダーゼ(XO)『血清尿酸値を上昇させる食生活』/循環器内科 87 (1): 95-101/共著/2020.01
講演 『知っておきたいプリン体の話 〜腎臓を守り、健康を保つために〜』/亀岡市医師会市民公開講座/単著/2019.11
講演 シンポジウム「子育て世代と共生する―すべての人が働きやすい 環境づくりのために―」/第53回 日本実験動物技術者協会総会 in 松山/共著/2019.10
講演 『尿酸と尿路結石〜再発予防に向けて〜。』/第30回 痛風・尿酸研修会/単著/2019.09
講演 国際学会シンポジウム“Women in Science”/The 6th International Symposium on Bioimaging & The 28th Annual Meeting of the Bioimaging Society/共著/2019.09
総説 特集 高尿酸血症と痛風における生活指導の最前線 —「高尿酸血症・痛風の治療ガイドライン第3版」より/臨床栄養 135 (2): 177-183/共著/2019.09
総説 プリン体の測定と食事療法への応用/痛風と尿酸・核酸 43 (1): 1-9/共著/2019.07
WEB講義『痛風・高尿酸血症(ガイドライン第3版に準じて)』/医療教育研究所にで収録/単著/2019.06
会長講演 『プリン代謝研究と尿路結石の微細分析』/第52回 日本痛風・核酸代謝学会(帝京大学板橋キャンパスにて)/単著/2019.02
総説 「巻頭グラビア」目でみる 食事療法シリーズ/高尿酸血症と痛風 21(2): 109-112〜 25(1):1-6/共著/2017.03
Determination of Total Purine and Purine Base Content of 80 Food products to Aid Nutritional Therapy for Gout and Hyperuricemia./Nucleosides Nucleotides Nucleic Acids.doi: 10.1080/15257770.2020.1748197/共著/2020.04
Trial Analysis of Drug Profiling by Liquid Chromatography/Mass Spectrometry and Inductively Coupled Plasma Mass Spectrometry to Establish the Origin of Ephedrines Used as Precursors for Illicit Production of Methamphetamine./Rapid Commun Mass Spectrom, 33 (11), 995-1005/共著/2019.06
Determination of Dipicolinic Acid in "Natto" by High- Performance Liquid Chromatography Coupled With Postcolumn Photoirradiation With Zinc Acetate./Int J Tryptophan Res.doi: 10.1177/1178646919852120./共著/2019.06
Proteomic analysis of a urinary stone with two layers composed of calcium oxalate monohydrate and uric acid./Nucleosides Nucleotides Nucleic Acids.2018;37(12):717-723/共著/2018.07
In vitro enhancement of ATP in human erythrocytes from a healthy subject and two patients with thalassemia and hemoglobinopathy./Gout and Nucleic Acid Metabolism 42 (1): 59-64/共著/2018.05
The observed variation in the purine composition of food after soaking in sake lees./Nucleosides Nucleotides Nucleic Acids. 2018;37(6):348-352/共著/2018.05
Simultaneous quantification by HPLC of purines in umami soup stock and evaluation of their effects on extracellular and intracellular purine metabolism./Nucleosides Nucleotides Nucleic Acids. 2018;37(5):273-279./共著/2018.05
Clinical studies on changes in purine compounds in blood and urine by the simultaneous administration of febuxostat and inosine, or by single administration of each./Gout and Nucleic Acid Metabolism 141 (2): 171-181/共著/2017.05
Evaluation of cellular purine transport and metabolism in the Caco-2 cell using comprehensive high-performance liquid chromatography method for analysis of purines./Nucleosides, Nucleotides and Nucleic Acids 35(10-12): 663-669/共著/2016.12
Urinary excretion of uric acid, allantoin, and 8-OH-deoxyguanosine in uricase-knockout mice./Nucleosides, Nucleotides and Nucleic Acids 35(10-12): 559-565/共著/2016.12
Analysis of l-DOPA-derived melanin and a novel degradation product formed under alkaline conditions./Journal of Pharmaceutical and Biomedical Analysis. 125: 22-26/共著/2016.03
Targeting uric acid and the inhibition of progression to end-stage renal disease -A propensity score analysis./PLoS One. 10(12):e0145506. doi: 10.1371/journal.pone.0145506/共著/2015.12
Proteomic Analysis after Sequential Extraction of Matrix Proteins in Urinary Stones Composed of Calcium Oxalate Monohydrate and Calcium Oxalate Dihydrate./Ana Sci 31(9): 935-942/共著/2015.09
Analysis of Intra- and Extracellular Levels of Purine Bases, Nucleosides, and Nucleotides in HepG2 cells by High-performance Liquid Chromatography./Anal Sci 31(9): 895-901/共著/2015.09
Proteomic analysis to examine the role of matrix proteins in a gouty tophus from a patient with recurrent gout./Nucleosides, Nucleotides and Nucleic Acids, 33: 199-207/共著/2014.12
Proteomic analysis of a rare urinary stone composed of calcium carbonate and calcium oxalate dihydrate: A case report./Int J Urol, 21: 341-346/共著/2014.05
Total purine and purine base content of common foodstuffs for facilitating nutritional therapy for gout and hyperiricemia./Biological and Pharmaceutical Bulletin 37 (5): 709-721/共著/2014.05
Metabolic Interactions of Purine Derivatives with Human ABC Transporter ABCG2: Genetic Testing to Assess Gout Risk.(/Pharmaceuticals 2013, 6, 1347-1360, doi:10.3390/ph6111347/共著/2013.05
Comparison of matrix proteins in different types of urinary stone by proteomic analysis using liquid chromatography–tandem mass spectrometry./Int J Urol., 19(8), 765-772/共著/2012.08
Sensitive Analysis of Sialic Acid and Related Compound by Hydrophilic Interaction Liquid Chromatography Using Fluorescence Detection after Derivatization with DBD-PZ./Anal. Sci. 34: 841-844/共著
七訂 食品成分表2020資料編/女子栄養大学出版部/共著/2020.02
すべての診療科で役立つ栄養学と食事・栄養療法/羊土社/共著/2019.01
高尿酸血症・痛風の治療ガイドライン第3版/診断と治療社/共著/2018.12
代謝センシング/シーエムシー出版/共著/2018.09
薬学テキストシリーズ 分析化学II/朝倉書店/共著/2018.03
スマート栄養管理術123/医歯薬出版株式会社/共著/2014.01
尿路結石症のすべて/医学書院/共著/2008.08
健康とくすりシリーズ『痛風予防のABC』/薬事日報社/単著/2008.07
主な担当授業科目名 物理化学、臨床検査学