小川 裕子
Faculty

学部・大学院

小川 裕子

所属 薬学部 薬学科 准教授
最終学歴 星薬科大学薬学部薬学科
現在所属している学会 日本生化学会、日本薬学会、日本唾液腺学会、毒素シンポジウム、日本内分泌撹乱化学物質学会
学士・修士・博士 博士(薬学)
所有資格 薬剤師免許、衛生検査技師免許、博士(薬学)、甲種危険物取扱者免許
研究の分野 生物系薬学
主な研究項目 分泌小胞エキソソームの機能解析、M1アミノペプチダーゼの基質特異性に関与する残基の探索と検討
主な研究業績 SARSウィルスの遺伝子の解明:その正体は?(査読付)/日本薬学会 ファルマシア TOPICS P1089-1090/単著/2003.11
27.Contribution of the exosome-associated form of secreted endoplasmic reticulum aminopeptidase 1 to exosome-mediated macrophage activation./Biochim Biophys Acta. 1865(6):874-888(2018)/共著/2018.06
26.Characterization of Membrane Integrity and Morphological Stability of Human Salivary Exosomes./Biol Pharm Bull., 40(8):1183-1191(2017)/共著/2017.08
25. Next-Generation Sequencing of Protein-Coding and Long Non-protein-Coding RNAs in Two Types of Exosomes Derived from Human Whole Saliva.(査読付)/Biol Pharm Bull., 39(9):1496-507(2016)/共著/2016.09
24.Migration of nonylphenol and plasticizers from polyvinyl chloride stretch film into food simulants, rapeseed oil, and foods(査読付)/Food Science & Nutrition 1–9 (2016)/共著/2016.06
Involvement of Phenylalanine 297 in the Construction of the Substrate Pocket of Human Aminopeptidase B (査読付)/Biochemistry 6;54(39):6062-70 (2015)/共著/2015.10
22.Role of glutamine-169 in the substrate recognition of human aminopeptidase B(査読付)/Biochim Biophys Acta. 1840(6):1872-81 (2014)/共著/2014.06
21.Small RNA transcriptomes of two types of exosomes in human whole saliva determined by next generation sequencing(査読付)/Biol Pharm Bull. 36(1):66-75 (2013)/共著/2013.01
20. Proteomic analysis of two types of exosomes in human whole saliva(査読付)/Biol Pharm Bull. 34(1):13-23 (2011)/共著/2011.01
19. Selective accumulation of a novel antimalarial rhodacyanine derivative,SSJ-127(査読付)/Bioorganic & Medicinal Chemistry18 7804–7808 (2010)/共著/2010.01
18.Molecular cloning and characterization of ecto-5'-nucleotidase from the venoms of Gloydius blomhoffi(査読付)/Toxicon.,54(4):408-412(2009)/共著/2009.01
17.Exosome-like vesicles with dipeptidyl peptidase IV in human saliva(査読付)/Biol Pharm Bull.,31(6):1059-1062(2008)/共著/2008.01
16.Exosome-like vesicles in Gloydius blomhoffii blomfoffii venom(査読付)/Toxicom.,51(6)984-993(2008)/共著/2008.01
15.Characterization and cDNA cloning of aminopeptidase A from the venom of Gloydius blomhoffi brevicaudus(査読付)/Toxicon.,49(8):1172-1181(2007)/共著/2007.01
14.Characterization and cDNA cloning of dipeptidyl peptidase IV from the venom of Gloydius blomhoffi brevicaudus(査読付)/Comp Biochem Physiol B Biochem Mol Biol.,145(1):35-42(2006)/共著/2006.01
13.Estrogenic activities of chemicals related to food contact plastics and rubberes tested by the yeast two-hybrid assay(査読付)/Food Addit. Contam.,23(4):422-430(2006)/共著/2006.01
12.Molecular cloning of the major lethal toxins from two kraits (Bungarus flaviceps and Bunggarus candidus)(査読付)/Txicon.47(4):416-424(2006)/共著/2006.01
11.On a salmon (Onchorhychus keta) liver RNase, belonging to RNase T2 family:primary structure and some properties(査読付)/Biosci Biotechnol Biochem.,69(2):343-352(2005)/共著/2005.01
10.Complate amino acid sequence and phylogenetic analysis of a long-chain neurotoxin from the venom of the African banded water cobra, Boulengerina annulata(査読付)/Toxicon.,43(7):855-858(2004)/共著/2004.01
9.Isolation, Toxicity and Amino Terminal Sequences of Three Maijor Neurotoxins in the Venom of Malayan Krait (Bungarus candidus) from Thailand(査読付)/J Biochem (Tokyo).,134(6):799-804(2003)/共著/2003.01
8.Estrogenic activities of UV stabilizers used in food contact plastics and benzophenone derivatives tested by yeast two-hybrid assay(査読付)/J.Health.Sci.,49:205-212(2003)/共著/2003.01
ウシガエル卵由来シアル酸結合レクチン(cSBL)の腫瘍細胞成長阻害作用増強化と作用機序(査読付)/単著/2002.07
7.Effect of replacing the aspartic acid/glutamic acid residues of bullfrog sialic acid binding lectin with asparagine/glutamine and arginine on the activity to inhibition of cell proliferation in murine leukemia P388 cells(査読付)/Biol.Pharm.Bull.,25:722-727(2002)/共著/2002.01
6.Enzymatic properties of sialic acid binding lectin from Rana catesbeiana modified with a water-soluble carbodiimide in the presence of various nucleophiles(査読付)/Biol.Pharm.Bull.,24:1366-1369(2001)/共著/2001.01
5.Effect of modification of the carboxyl groups of the sialic acid binding lection from bullfrog (Rana catesbeiana) oocyte on the anti-tumor activity.(査読付)/Biol.Pharm.Bull.,24:978-981(2001)/共著/2001.01
4.Amino acid sequence and characterization of a rice bran ribonuclease(査読付)/Biol.Pharm.Bull.,24:760-766(2001)/共著/2001.01
3.A protease sensitive region of plant and animal ribonuclease belonging to RNase T2 family(査読付)/Biol.Pharm.Bull.,21:634-637(1998)/共著/1998.01
2.Bovine spleen acid ribonuclease is a member of the T2 family(査読付)/J.Biochem.Biol. & Biophys.,1:21-26(1997)/共著/1997.01
1.Enzymatic activities of several K108 mutants of ribonuclease (RNase) Rh isolated from Rhizopus niveus (査読付)/Biol.Pharm.Bul.,19:1080-1082(1996)/共著/1996.01
主な担当授業科目名 化学物質と健康、化学系実習II、衛生薬学特論、薬学総括講義IV